A case series of pseudoxanthoma elasticum-like disorders

Pseudoxanthoma elasticum-like papillary dermal elastolysis: a large case series with clinicopathological correlation.

BACKGROUND Pseudoxanthoma elasticum (PXE)-like papillary dermal elastolysis (PDE) is a rare acquired elastic tissue disorder. To date, less than 20 cases have been reported. OBJECTIVE We report a case series of 17 patients presenting with PXE-like PDE and discuss the clinicopathological correlation. METHODS Seventeen cases of PXE-like PDE were collected prospectively and evaluated for commo...

Pseudoxanthoma elasticum

Pseudoxanthoma elasticum (PXE) is a genetic metabolic disease with autosomal recessive inheritance caused by mutations in the ABCC6 gene. The lack of functional ABCC6 protein leads to ectopic mineralization that is most apparent in the elastic tissues of the skin, eyes and blood vessels. The clinical prevalence of PXE has been estimated at between 1 per 100,000 and 1 per 25,000, with slight fem...

Pseudoxanthoma elasticum

Pseudoxanthoma elasticum-like papillary dermal elastolysis*

An Bras Dermatol. 2017;92(6):891-900. According to the literature, hospitalization is required in some cases, which did not happen in our case because of the early intervention (Table 2).5 Considering a reduced risk of agranulocytosis development and in accordance with Carneiro et al. (2011),5 our aim was not to question DDS therapy for leprosy, but to stimulate clinical awareness of its risks ...

Arms Lift in a Case of Pseudoxanthoma Elasticum

Pseudoxanthoma elasticum (PXE) is a rare hereditary disorder of elastin fibers, characterized by yellowish coalescent papules in flexural surfaces with abnormally lax and corrugated skin. It can be associated to systemic manifestations mostly regarding eyes and vessels. Aesthetic surgery of cutaneous hyperlaxity was described in the international literature only in few cases, mostly as neck lif...